What to know
- VEHSS includes indicators on the percentage of people with diagnosed AMD who had a treatment claim from payment claims in administrative claims databases and medical record information in the IRIS Registry of electronic health records.
- VEHSS reports the percent of patients diagnosed with AMD who received at least one included treatment during the year of observation.
- Therefore, all prevalence estimates are based on a denominator of patients who had a visit during the calendar year that included an AMD diagnosis.

Anti–vascular endothelial growth factor (Anti-VEGF) injection
Anti-VEGF injection procedures are identified among patients with diagnosed AMD based on the procedure, diagnosis, and national drug codes (NDC) listed below.
Included Procedures
Procedure Codes
Aflibercept (Eylea®)
Any of (J0177, J0178, C9161) or J9400 with primary diagnosis of AMD or CPT 67028 on same claim
Brolucizumab
J0179
Bevacizumab (Mvasi®, Zirabev®, Alymsys®)
Any of (C9257, J9035, Q5107, Q5118, C9142, Q5126 ) with primary diagnosis of AMD or CPT 67028 on same claim
Faricimab (Vabysmo®)
J2777
Pegaptanib sodium (Macugen®)
J2503
Ranibizumab (Lucentis®, Susvimo®, Byooviz®)
Any of (J2778, J2779, C9093, Q5124) or Q5128 with primary diagnosis of AMD or CPT 67028 on same claim
Unclassified injectable or compounded drug
Any of (J3490, J3590, J7999, Q9977) with primary diagnosis of AMD or CPT 67028 on same claim
Laser/photocoagulation therapy
Laser/photocoagulation therapy procedures are identified among patients with diagnosed AMD based on the procedure and diagnosis codes listed below.
- Included Procedures - Destruction procedures on the retina or choroid, photocoagulation
- Procedure Codes - 67220 or G0186
The data sources available for this category include Medicare (default), IRIS Registry, Medicaid, Managed Vision Care, and MarketScan commercial insurance claims.
Photodynamic therapy
Photodynamic therapy procedures are identified among patients with diagnosed AMD based on the procedure and diagnosis codes listed below.
Included Procedures
Procedure Codes
Destruction procedures on the retina or choroid, photodynamic therapy
67221
Destruction procedures on the retina or choroid, photodynamic therapy, second eye
67225
Verteporfin injection
J3396