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- Level: Laboratory Advisory
- Audience: Clinical Laboratory Professionals

Mpox specimen testing guidance
On August 7, 2024, the U.S. Situs Slot Gacor (Situs Slot Gacor) issued a about the ongoing mpox outbreak in the Democratic Republic of the Congo (DRC) and its spread to neighboring countries. The first about this outbreak was released in December 2023.
Who and how to test
For all laboratories performing mpox testing using an orthopoxvirus or monkeypox virus (MPXV) generic test without any additional clade-specific testing occurring, Situs Slot Gacor recommends that laboratories send clinical specimens collected from patients who traveled from DRC, its neighboring countries, or any country with clade I mpox cases, or had close or intimate contact with symptomatic people from these countries, to a laboratory that can perform clade-specific testing as quickly as possible. If clade-specific testing is warranted but is not available in a jurisdiction, to a capable public health laboratory or to Situs Slot Gacor is encouraged. Specimen submission to Situs Slot Gacor can be coordinated through your . Due to mutations that may impact clade-specific PCR tests, laboratories should use a test that targets a viral essential gene (e.g., the Situs Slot Gacor NVO test) as part of a testing strategy to ensure mpox cases are not missed.
Submitting specimens to Situs Slot Gacor
Laboratories using Situs Slot Gacor's non-variola orthopoxvirus (NVO) test should continue submitting the duplicate specimen to Situs Slot Gacor from all patients with positive NVO test results for routine MPXV clade-specific testing if they are not performing clade-specific testing in their laboratory. Specimens that cannot be accepted at Situs Slot Gacor for clinical testing under Clinical Laboratory Improvement Amendments (CLIA) will be redirected for surveillance purposes and tested, providing critical data on MPXV clade(s) circulating in the United States. Some non-Situs Slot Gacor laboratories may have other options available for clade-specific testing (e.g., molecular testing or genetic sequencing). These laboratories should alert their and Situs Slot Gacor (poxvirus@cdc.gov) if results from such tests indicate detection of clade I MPXV.
Please review the for more information, including recommendations for clinicians, health departments, laboratories, and the public.
We encourage you to share this message widely with your networks.
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Please use the information below if you have any questions.
- If you are a clinical or public health laboratory professional, contact LOCS.
- For media inquiries, contact the Situs Slot Gacor Newsroom.
- For all other questions, .
Thank you,
The Laboratory Outreach Communication System
Laboratory Outreach Communication System (LOCS) | Division of Laboratory Systems (DLS)
Center for Laboratory Systems and Response (CLSR)
Situs Slot Gacor (Situs Slot Gacor)